Ghana
Active polio, cholera, typhoid and influenza WES with regional AMR leadership. Detailed cost and coverage data still being collected.
Today vs the 5-year target
- Active sites
- —
- Provinces covered
- — / 16
- Population coverage
- —
- Cost / sample
- —
- Active sites
- 30+
- Provinces covered
- 16 / 16
- Population coverage
- 25%
- Cost / sample
- —
TBC
What is being tracked today
- Poliovirus integrated
- Cholera integrated
- Salmonella Typhi integrated
- Influenza integrated
- SARS-CoV-2 researched
- E. coli researched
- Antimicrobial Resistance (AMR) researched
- Hepatitis A/E researched
What it costs to monitor
Strengths and challenges
- Sewer coverageModerate
- LogisticsModerate
- Testing capacityHigh
- Use of informationModerate
- Cost & valueModerate
- Ghana has a strong, nationally-recognised laboratory capacity at NMIMR with WES implementation experience and can run multi-pathogen surveillance (Polio, Cholera, Typhoid and Influenza) from a single sample.
- Ghana has a clearly structured public health delivery system from national, regional to district level. A ready-made implementation framework for scaling WES.
- Ghana has the highest integration rate of the five countries, with all four surveyed pathogens formally integrated into national disease surveillance.
- Existing cross-sectoral relationships between NMIMR, Ghana Health Service, Environmental Protection Agency and water utilities provide a foundation for One Health coordination.
- Ghana has an existing and funded AMR-WES programme that is a component of a $16M Pandemic Fund grant.
- Programme scale, site numbers, geographic coverage, and unit costs are still being established, limiting the ability to build a credible investment case or targets.
- The sampling methodology for non-sewered, peri-urban, and rural settings is underdeveloped, creating a representativeness gap as a significant proportion of the population live in these areas.
- WES data management and reporting systems are not standardised yet with inconsistencies in how data is recorded, stored and reported across institutions.
- Whilst NMIMR has strong capacity, Ghana relied on external technical assistance for advanced sequencing and genomic analysis, creating a potential bottleneck.
- Strong political incentives to invest in WES due to Ghana's regional leadership position on AMR surveillance. Widely recognised leader on AMR across West Africa.
- Diversified financing base provided by the multiple active and interested donors (World Bank, AfDB, Pandemic Fund, USAID, EU).
- Stable democratic governance and functional public financial management systems reduce fiduciary and implementation risk for external funders.
- Alignment with Africa CDC's integrated disease surveillance agenda provides a continental policy anchor. Strengthening the political case for WES both domestically and internationally.
- WES remains vulnerable to reprioritisation when competing health demands arise as no dedicated national WES policy, strategy or mandate exists.
- Political transitions have created continuity risk for health sector priorities, meaning surveillance investments and programme momentum stall.
- Responsibility sits across NMIMR, GHS, EPA, and water utilities with no designated lead agency, creating coordination fragmentation and making a scale-up challenging.
- Ghana operates under an IMF-supported debt restructuring programme that limits new government expenditure across sectors.
- Risk of losing access to financing windows before domestic revenues are sufficient to replace them as the country moves towards upper-middle-income status.
Where the funding could come from
- Domestic government expenditurepossible
Stronger fiscal position. Expansion possible if WES integrated into national health plan.
- World Bank IDApossible
Could explore new IDA project framed around health system strengthening.
- European Investment Banklikely
EIB building health commodity capacity in Africa. Ghana's governance framework makes it attractive.
- Pandemic Fundpossible
Existing $16M PF grant can be leveraged for AMR-WES integration where Ghana holds regional leadership.
- IPSN (WHO Pathogen Surveillance Network)likely
Ghana holds regional AMR leadership and has existing genomic surveillance capacity. Strong alignment with IPSN's One Health and pathogen genomics agenda.
- The Global Fundpossible
GF active in Ghana. WES could be integrated into existing grant structures if in national health strategic plan.
- Gates Foundationpossible
Gates active in Ghana health sector. WES investment would need to align with integrated disease surveillance agenda.
- Rotary Foundationpossible
Possible for polio-linked WES investment.
- Bilateral GHS donorspossible
Active bilateral donors in Ghana. WES framed as pandemic preparedness aligns well.
What to do next
- Leverage Ghana's existing $16M Pandemic Fund grant to integrate AMR-WES into national surveillance — building on Ghana's regional leadership in One Health.Cost: low Timeline: immediate
- Develop a cost-effectiveness analysis for WES multi-pathogen scale-up — to support the case for domestic government expenditure expansion.Cost: low Timeline: immediate
- Integrate SARS-CoV-2 WES into national surveillance system — building on existing polio/cholera/typhoid/influenza infrastructure.Cost: medium Timeline: short
- Explore IDA project vehicle for WES lab strengthening — if structured around health system strengthening with strong MoH ownership.Cost: high Timeline: medium